Gut dysbiosis, marked by diminished microbial diversity and imbalanced bacterial composition, is a hallmark of Alzheimer’s disease (AD) AD often emerges in prodromal stages like mild cognitive impairment (MCI) and contributes to pathogenesis through the microbiota-gut-brain axis. AD patients show consistent reductions in short-chain fatty acid (SCFA)-producing taxa and enrichments in pro-inflammatory genera, correlating with […]
Gut dysbiosis is characterized by reduced microbial diversity and shifts in bacterial composition. It is a prominent feature in Parkinson’s disease (PD), often preceding motor symptoms by years and contributing to disease initiation and progression via the microbiota-gut-brain axis. PD patients exhibit consistent alterations, including depletion of short-chain fatty acid (SCFA)-producing bacteria and enrichment of […]
Short-chain fatty acids (SCFAs), including acetate, propionate, and butyrate, emerge as promising therapeutic agents in Parkinson’s disease (PD). They target the gut-brain axis, mitigating alpha-synuclein (α-syn) pathology, reducing neuroinflammation, and enhancing dopaminergic function. PD patients exhibit gut dysbiosis with reduced SCFA-producing bacteria (e.g., Faecalibacterium prausnitzii, Roseburia spp.) and lower fecal/plasma SCFA levels, correlating with motor […]
Dementia: Pathways to Prevention Dementia, a progressive decline in cognitive function that affects memory, thinking, and daily activities, is a growing global concern. While there is no cure, emerging research offers strong evidence that a significant portion—up to 45%—of dementia cases could potentially be prevented or delayed through lifestyle modifications targeting modifiable risk factors. thelancet.com […]
Breast Cancer Risk Factors and Recent Developments According to a September 22, 2025 CDC post, breast cancer risk factors are divided into modifiable and non-modifiable categories: Modifiable: Increasing physical activity, reducing alcohol consumption, limiting hormone intake, and maintaining a healthy weight. Non-modifiable: Genetic mutations, dense breast tissue, family history of breast or ovarian cancer, and […]
Aristotle’s view of the good life, or eudaimonia, is living virtuously in accordance with reason, fulfilling one’s potential through moral and intellectual excellence, and finding balance in all things. His principles are part of the Harvard Medical School’s Lifestyle and Wellness coaching program as well as the DreamBuilding® Life Transformation program. To live the good […]
Sleep involves a complex interplay of physiological processes that restore and regulate the body, orchestrated by the brain and influenced by hormones like melatonin. Below, I’ll outline the key body processes during sleep, the role of melatonin, and address whether organs are “updated” at specific times. Our Body Processes During Sleep Sleep is divided into […]
Smoking is bad for you, no matter what new, fancy, and fashionable ways they invent to keep us hooked in an illusion of prestige and feeling good about ourselves. It mainly starts in childhood (the best victims are children) from a desire to look older, and it is a totally addictive habit that should never […]
The role of the vagus nerve in regulating inflammation and its broader implications for immunity and metabolism have been analyzed by Valentin A. Pavlov and Kevin J. Tracey in the article, “The vagus nerve and the inflammatory reflex—linking immunity and metabolism.” The two scientists describe the inflammatory reflex as a neural circuit where the vagus […]
The connection between our gut microbiome and mental health is a reality. Depressive disorder (like major depression), generalized anxiety disorder, bipolar disorder, and eating disorders (such as anorexia nervosa or bulimia) are all linked to the gut microbiome—the trillions of bacteria and other microbes living in our intestines. These connections happen mainly through the gut-brain […]