High-Intensity Interval Training for Health

HIIT stands for High-Intensity Interval Training
It is the #1 Hormetic Biohack for Mitochondria, Fat Loss, and Longevity


1. HIIT in 1 Sentence

HIIT = alternating bursts of near-max effort (80–95% HRmax) with short recovery periods — the fastest way to upgrade your mitochondria, burn fat, and extend lifespan.

2. HIIT vs. Steady-State Cardio

Metric
HIIT (4×4)
Moderate Cardio (LISS)
Time
20–30 min
45–60 min
Calories Burned (24 h)
+15–20% EPOC
Baseline
Mitochondrial Density
+50–100% PGC-1α
+10–20%
VO₂max Gain
+10–15% in 6 wks
+5–8%
Fat Loss
3× more visceral fat
Moderate
Hormesis
Strong (ROS → Nrf2)
Mild

3. GOLD-STANDARD HIIT PROTOCOLS(Pick ONE — rotate every 4–6 wks)

Protocol
Work: Rest
Total Time
Best For
1. 4×4 (Norwegian)
4 min @ 90–95% HRmax → 3 min @ 60% ×4
28 min
VO₂max, longevity
2. Tabata
20 sec ALL-OUT → 10 sec rest ×8
4 min
Anaerobic power
3. 30/30
30 sec sprint → 30 sec walk ×10–15
10–15 min
Beginners, fat loss
4. 10×1
1 min @ 85% → 1 min recovery ×10
20 min
Hybrid strength

4. HOW TO DO THE 4×4 (STEP-BY-STEP)The most studied, most effective

  1. Warm-up: 5 min light jog/cycle (50% effort)
  2. Interval 1:
    • 4 min @ 90–95% HRmax (can barely talk)
    • HR target: 220 – age × 0.9–0.95
  3. Recovery: 3 min @ 60% (conversational pace)
  4. Repeat ×4 total intervals
  5. Cool-down: 3–5 min easy

Equipment: Treadmill, bike, rower, hill sprints, or bodyweight (burpees, air squats)


5. HRmax CHEAT SHEET (220 – age = estimated max)

Age
HIIT Zone (90–95%)
30
171–180 bpm
40
162–171 bpm
50
153–162 bpm
60
144–153 bpm

No watch? Use RPE:

  • 9/10 effort = “I’m dying in 30 sec”
  • 6/10 recovery = “I can chat”

6. HIIT + HORMESIS (Why It Works)

Stress Signal
Adaptive Response
Long-Term Win
↑ Lactate
↑ PGC-1α, ↑ mito biogenesis
+Energy
↑ ROS (transient)
↑ Nrf2 → SOD, GPx
+Antioxidant armor
↑ AMPK
↑ Fat oxidation, ↓ mTOR
+Fat loss, longevity
↑ BDNF
↑ Neurogenesis
+Brain health

7. BEGINNER HIIT (Start Here) If 4×4 scares you

Week
Protocol
1–2
30 sec work / 90 sec walk ×6–8
3–4
45 sec / 75 sec ×8
5+
Graduate to 30/30 or 4×4

8. HIIT RED FLAGS (Stop & Recover)

Sign
Fix
Dizziness, nausea
Hydrate, carbs pre-workout
HR > 100 bpm after 5 min recovery
Deload 1 week
Joint pain
Switch to bike/rower
Sleep ↓, HRV ↓
Cut to 2×/wk

9. SAMPLE WEEK (Plug & Play)

Day
HIIT
Recovery
Mon
4×4 (bike)
Walk 20 min
Tue
Strength (full body)
Wed
OFF
Yoga
Thu
Tabata (bodyweight)
Fri
4×4 (run)
Sat
OFF
Sauna
Sun
Light Zone 2 (45 min)

10. PRO TIPS

  1. Pre-HIIT Fuel: 10–20 g carbs (banana) 15 min before
  2. Post-HIIT: 20 g protein + 30 g carbs within 30 min
  3. Track: Use Strava or Apple Fitness (HIIT mode)
  4. Progress: Add 1 interval every 2 weeks

Your First HIIT Session (4 min)

Try this NOW (Tabata):

  • 20 sec burpees → 10 sec rest ×8
  • Total: 4 min
  • Result: ↑EPOC, ↑mitochondria, ↑mood

HIIT = the shortest path to a younger metabolism.
Do 2–3 sessions/wkfeel the difference in 7 days.
TABATA WORKOUT
HIIT VIDEO

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