FOLATE-RICH DESSERT SMTX-Friendly Treats Print & Enjoy! 50–150 mcg folate per serving | No added sugar overload | <15 min prep 1. Avocado-Chocolate Mousse (~90 mcg folate) Serves 2 | 5 min Ingredient Amount Ripe avocado 1 medium Cocoa powder (unsweetened) 2 tbsp Maple syrup or honey 1–2 tbsp Vanilla ½ tsp Milk (any) 2–3 […]
METHOTREXATE (MTX) & FOLIC ACID Patient Handout – Print & Take to Your Doctor Name: _________________________MTX Dose: ______ mg weekly on ________ (day)Folic Acid Plan: □ 5 mg once weekly on ________ (day) □ 1 mg daily (except MTX day) Why You Need Folic Acid MTX blocks folate → causes side effects like mouth sores, nausea, […]
Methotrexate (often abbreviated as MTX) is a medication commonly used to treat conditions like rheumatoid arthritis (RA), juvenile idiopathic arthritis (JIA), psoriasis, and certain cancers.It works by inhibiting the enzyme dihydrofolate reductase, which interferes with folate metabolism. While effective, this mechanism can lead to deficiencies in several vitamins, particularly those in the B-vitamin family and […]
What are Short-Chain Fatty Acids (SCFAs) and what role do they play in our overall health? They play an enormous role in our health, encompassing gut health, metabolism, immunity, cardiovascular health, musculoskeletal health, neurological health, and mental health and wellbeing. Short-chain fatty acids (SCFAs), mainly acetate, propionate, and butyrate, are produced by our gut microbiota […]
Short-chain fatty acids (SCFAs), such as acetate, propionate, and butyrate, exhibit broad therapeutic potential across multiple disease categories, including neurodegenerative and demyelinating conditions. They primarily act through mechanisms like G-protein-coupled receptor (GPCR) activation (e.g., GPR41/43/109A), histone deacetylase (HDAC) inhibition, anti-inflammatory effects (e.g., Treg promotion, NF-κB suppression), and metabolic regulation (e.g., AMPK activation for lipid/glucose homeostasis). […]
Short-chain fatty acids (SCFAs), including acetate, propionate, and butyrate, emerge as promising therapeutic agents in Alzheimer’s disease (AD). Short-chain fatty acids are produced by gut microbiota fermentation of dietary fibers. These SCFAs play a complex role in Alzheimer’s disease (AD) through the microbiota-gut-brain axis. AD patients exhibit gut dysbiosis with reduced SCFA-producing bacteria (e.g., Faecalibacterium […]
Gut dysbiosis, marked by diminished microbial diversity and imbalanced bacterial composition, is a hallmark of Alzheimer’s disease (AD) AD often emerges in prodromal stages like mild cognitive impairment (MCI) and contributes to pathogenesis through the microbiota-gut-brain axis. AD patients show consistent reductions in short-chain fatty acid (SCFA)-producing taxa and enrichments in pro-inflammatory genera, correlating with […]
Gut dysbiosis is characterized by reduced microbial diversity and shifts in bacterial composition. It is a prominent feature in Parkinson’s disease (PD), often preceding motor symptoms by years and contributing to disease initiation and progression via the microbiota-gut-brain axis. PD patients exhibit consistent alterations, including depletion of short-chain fatty acid (SCFA)-producing bacteria and enrichment of […]
Short-chain fatty acids (SCFAs), including acetate, propionate, and butyrate, emerge as promising therapeutic agents in Parkinson’s disease (PD). They target the gut-brain axis, mitigating alpha-synuclein (α-syn) pathology, reducing neuroinflammation, and enhancing dopaminergic function. PD patients exhibit gut dysbiosis with reduced SCFA-producing bacteria (e.g., Faecalibacterium prausnitzii, Roseburia spp.) and lower fecal/plasma SCFA levels, correlating with motor […]
Breast Cancer Risk Factors and Recent Developments According to a September 22, 2025 CDC post, breast cancer risk factors are divided into modifiable and non-modifiable categories: Modifiable: Increasing physical activity, reducing alcohol consumption, limiting hormone intake, and maintaining a healthy weight. Non-modifiable: Genetic mutations, dense breast tissue, family history of breast or ovarian cancer, and […]