The gut microbiota refers to the diverse community of microorganisms (bacteria, fungi, viruses, etc.) residing in the gastrointestinal tract, which profoundly influences health, including brain function and barrier integrity. Below, I’ll provide a detailed overview of the microbiota’s composition, functions, mechanisms of interaction with the BBB and vagus nerve, and recent research findings, integrating insights […]
This is an overview of probiotics for Alzheimer’s disease (AD), focusing on their mechanisms, recent research (2020–2025), and connections to the BBB (Blood-Brain Barrier) and vagus nerve. Probiotics are live microorganisms that, when administered in adequate amounts, confer health benefits, including potential neuroprotective effects in Alzheimer’s disease (AD). This article integrates insights and relevant findings, […]
Obesity occurs when energy intake from food consistently exceeds energy expenditure, leading to fat accumulation. This imbalance is influenced by genetics, diet, physical inactivity, gut microbiome, hormones, socioeconomic factors, and psychological triggers. An obesiogenic microbiome, high-calorie diets, and sedentary lifestyles amplify the issue, while insulin resistance and leptin dysfunction can perpetuate weight gain. It’s a […]
You can reverse obesity by getting rid of your obesiogenic microbiome and establishing healthy dietary and lifestyle habits. Here are a few key points: Research suggests dietary changes, like increasing fiber and adopting a Mediterranean diet, can help alter an obesiogenic microbiome. It seems likely that probiotics, prebiotics, and exercise also play a role in […]
To cultivate the most beneficial gut bacteria, such as Akkermansia muciniphila, Bifidobacterium species, Lactobacillus species, and others linked to health and longevity (e.g., Faecalibacterium prausnitzii), focus on evidence-based dietary, lifestyle, and environmental strategies. These bacteria support gut barrier function, reduce inflammation, produce short-chain fatty acids (SCFAs) like butyrate, and enhance overall health, as seen in […]
Centenarians, people aged 100 or older, often share these characteristics based on research and observations: Genetics: Strong genetic factors are present, with many individuals having family members who lived long lives. Lifestyle: Healthy diet, often plant-based with moderate portions (e.g., Mediterranean or Okinawan diets). Regular, low-intensity physical activity, such as walking or gardening. Limited smoking […]
Based on current research, there are ways to increase Akkermansia and Bifidobacterium in your gut. Focus on your nutrition, lifestyle, and, if necessary, supplements. For Akkermansia (Akkermansia muciniphila): Polyphenol-Rich Foods: Akkermansia thrives on polyphenols found in: Berries (blueberries, cranberries, pomegranate). Dark chocolate (70%+ cocoa). Red wine (in moderation) or grape skins. Green tea or black […]